Advanced Analytical Services for Patent Litigation Support

My services

Peak List Analysis - Peak Extraction

In patent litigation, precise numerical data is essential for material comparison. My peak list extraction service converts raw X-ray Powder Diffraction (XRPD) patterns into structured numerical data using parametric fitting techniques.

This process provides:

Peak positions (2θ values) – Identifying key diffraction angles.
Relative intensities – Capturing the strength of each peak for comparison.

I do not determine the full crystal structure but deliver high-precision peak data, enabling legal teams and experts to compare experimental samples with patented reference patterns. This is a critical step in assessing material similarity, identifying potential infringement, or demonstrating clear differences.

Fingerprinting

In pharmaceutical patent litigation, proving whether a drug product matches or differs from a patented formulation often hinges on phase identification through X-ray Powder Diffraction (XRPD). My fingerprinting service enables precise identification of each crystalline component within a sample, ensuring accurate material verification.

How It Works:

✅ Identification of APIs & Excipients
Given a drug’s diffraction pattern and a known list of its Active Pharmaceutical Ingredients (APIs) and excipients, I:

Compare the experimental XRPD pattern against reference patterns for each expected component.
Confirm whether all declared compounds are present in the correct crystalline forms.

✅ Impurity & Polymorph Detection
Beyond verifying expected ingredients, I analyze the diffraction pattern to:

Detect unexpected crystalline phases (e.g., unlisted excipients, contaminants, or foreign materials).
Identify the presence of alternative polymorphs, which may indicate infringement (if covered by a patent) or serve as a defense (if demonstrably different).
Rule out or confirm degradation products or phase transitions that could impact drug stability.

Pattern Comparison

I superimpose diffraction patterns to visually compare an alleged infringing material with a patented reference pattern, allowing for a detailed assessment of material similarities and differences.

✅ Highlight differences in peak positions and shapes.
✅ Detect additional or missing peaks that may indicate material discrepancies.
✅ Provide clear visual evidence to support or refute infringement claims.

My independent XRPD analysis ensures precise, litigation-ready comparisons to strengthen patent disputes.

Pattern Digitalization

Many patents present diffraction data as static images rather than numerical tables, making direct comparison challenging. My digitalization service accurately extracts peak data from patent diagrams, enabling:

✅ Conversion of graphical diffraction patterns into numerical peak lists.
✅ Direct comparison with experimental data for infringement analysis.
✅ Generation of synthetic reference patterns when no raw patent data is available.

This process ensures that patent diffraction data can be effectively utilized in legal proceedings, supporting precise and informed analysis.

Expert Reports & Litigation Support

My expert reports are tailored to meet the exacting standards of patent litigation, offering:

✅ Comprehensive technical analysis of diffraction patterns and peak lists.
✅ Clear, objective conclusions on material identity and potential infringement.
✅ Graphical overlays and visual evidence to support legal arguments.
✅ Expert witness testimony when required for depositions or court proceedings.

With a focus on clarity, scientific rigor, and legal admissibility, my reports are crafted to provide decisive, litigation-ready evidence for patent cases.

Tailored, Confidential, and Fast Analytical Services

I understand that every patent litigation case is unique. That’s why I offer customizable services tailored to meet the specific needs of your case, whether you're seeking detailed diffraction analysis, peak identification, or phase comparison.

I prioritize confidentiality in all aspects of my work, ensuring that your sensitive data and legal matters are handled with the highest standards of security. Additionally, I’m committed to providing fast turnaround times without compromising on accuracy, ensuring you receive court-ready reports when you need them.

My goal is to support your legal team with reliable, timely, and tailored analytical services, helping you navigate complex patent disputes with confidence.